Why the study?
Does antipsychotic drug use increase the risk of venous thromboembolism in elderly patients with dementia?
Population
5,137 elderly patients with dementia drawn from a cohort of 72,591 patients in the German…
Comparison
Antipsychotic drug use vs Nonusers of antipsychotic drugs
Design
Case-control
Authors
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May warrant VTE vigilance on antipsychotic initiation in dementia; leaves open causality and needs prospective confirmation.
Does antipsychotic drug use increase the risk of venous thromboembolism in elderly patients with dementia?
In elderly patients with dementia, the initiation of antipsychotics and the concurrent use of conventional and atypical agents are associated with a significantly increased risk of venous thromboembolism.
Schmedt et al. (2013) studied this question.
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