Right on target: A multifunctional nanoprobe is designed for target-cell-specific imaging and in situ detection of intracellular miRNA. The nanoprobe is prepared by functionalizing SnO2 nanoparticles with both folic acid (FA), a target-cell-specific moiety to recognize folate receptors overexpressed on cancer cells, and a gene probe to inhibit or recognize intracellular miRNA levels (see scheme).
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Dong et al. (2012) studied this question.
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