Population
3 patients with advanced colorectal carcinoma
Design
Case_series
Authors
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May prompt monitoring for hypotension and LV dysfunction with 5-FU; hypothesis-generating case reports leave open need for prospective validation.
Cisplatin and 5-fluorouracil therapy may cause cardiotoxicity manifesting as hypotension and severe left ventricular dysfunction.
Jakubowski et al. (1988) studied this question.
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