Why the study?
Is baroreflex sensitivity reduced and correlated with blood pressure variability in essential hypertensive patients compared to normotensive subjects?
Is baroreflex sensitivity reduced and correlated with blood pressure variability in essential hypertensive patients compared to normotensive subjects?
In essential hypertensive patients, baroreflex sensitivity is reduced and inversely correlates with systemic blood pressure variability.
Reduced baroreflex sensitivity associates with BP variability in hypertension; hypothesis-generating and requires prospective validation before clinical consideration.
We have monitored intra-arterial pressure continuously throughout the day and analysed every beat by computer. 2. Baroreflex sensitivity (ms/mmHg) was measured four times a day (07.00, 12.00, 17.00 and 20.00 hours) in seven patients and three times a day (07.00, 12.00 and 17.00 hours) in 23 patients. The diurnal variation of baroreflex sensitivity in individual patients was 0--5.3 ms/mmHg and was not consistent. Mean baroreflex sensitivity was reduced in hypertensive patients compared with normotensive subjects. 3. A negative correlation was seen between baroreflex sensitivity and the variability of systemic blood pressure. 4. Baroreflex sensitivity was well correlated with the variability of heart rate.
No takes yet. Share an insight, caveat, or question.
Ogawa et al. (1981) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: