Key result
Ambulatory pulse wave analysis shows a ~0.67 correlation with the phenylephrine method for baroreflex sensitivity.
Why the study?
The sensitivity of arterial baroreflex during daily activity and its dynamic changes according to reflex input were not well characterized.
Population
34 hypertensive and 4 normotensive subjects
Comparison
Baroreflex sensitivity by telemetry pulse wave analysis vs phenylephrine method
Design
Observational study with continuous ambulatory arterial pressure monitoring
Follow-up
24 hours
Authors
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Ambulatory baroreflex assessment may enable dynamic monitoring; leaves open prognostic value versus phenylephrine testing.
Observational (n=38)
Effect estimate: r = 0.667
p-value: p=<0.001
A computer analysis method using continuous ambulatory arterial pressure monitoring can dynamically measure arterial baroreflex sensitivity during daily activity, correlating well with the standard phenylephrine method.
Yamamoto et al. (1989) conducted an observational in Hypertension (n=38). Computer analysis of pulse wave from continuous ambulatory arterial pressure monitoring vs. Phenylephrine method was evaluated on Correlation of baroreflex sensitivity measured by computer analysis of pulse wave with the phenylephrine method (r = 0.667, p=<0.001). Baroreflex sensitivity measured by computer analysis of pulse wave from 24-hour ambulatory monitoring correlated significantly with the phenylephrine method (r = 0.667, P<0.001).