Why the study?
Dexmedetomidine prolongs local anesthetic effects, but its effect on the analgesic duration of ultrasound-guided fascia iliaca compartment block with bupivacaine for femur fracture surgery needed comparison against bupivacaine alone.
Does adding dexmedetomidine to bupivacaine in ultrasound-guided fascia iliaca compartment block prolong postoperative analgesia in patients with femur fractures?
Does adding dexmedetomidine to bupivacaine in ultrasound-guided fascia iliaca compartment block prolong postoperative analgesia in patients with femur fractures?
Adding dexmedetomidine to bupivacaine for ultrasound-guided fascia iliaca compartment block significantly prolongs postoperative analgesia and reduces rescue analgesic requirements in patients undergoing femur fracture surgery.
Supports adding dexmedetomidine to bupivacaine in fascia iliaca blocks for femur fractures; extends evidence on adjuvants in regional anesthesia.
Background : Femur fractures are extremely painful due to the lowest pain threshold of the periosteum among the deep somatic structures. Perioperative Fascia Iliaca Compartment Block (FICB), when administered using a local anesthetic agent, bupivacaine, can reduce morbidity by providing satisfactory pain relief. Dexmedetomidine, an alpha-2 agonist, is known to prolong the local anesthetic effects without causing any significant side effects. We compared analgesic duration of ultrasound guided FICB with bupivacaine alone and bupivacaine with dexmedetomidine for postoperative analgesia. A prospective, randomized, double blinded study was conducted on 50 patients Materials And Method: aged 18 to 65 years undergoing femur fracture surgeries. Patients were divided into 2 groups of 25 each. Both groups received USG guided FICB. Group A received 28 ml 0.25% bupivacaine and 2 ml normal saline (NS). Group B received 28 ml 0.25% bupivacaine and 30 mcg dexmedetomidine in NS. Pain scores were assessed every 5 minutes until 15 minutes post FICB, during positioning for subarachnoid block and every 2 hours until 24 hours post-operatively. Total duration of analgesia, cumulative analgesia requested in 24 hours, Ramsay sedation and patient satisfaction scores were recorded. Results: The mean duration of analgesia in Group A was 419.4 ± 115.35 minutes (95%CI: 374.2 – 464.6) and in Group B was 656.6 ± 137.99 minutes (95%CI: 602.5 –710.7), p <0.001. Mean VAS score during positioning for SAB in Group A was 1.60 ± 0.50 and in Group B was 0.96 ± 0.68. USG guided FICB with dexmedetomidine is superior in Conclusion: providing prolonged post-operative analgesia in comparison to bupivacaine alone
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Muniyappa et al. (2023) studied this question.
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