Why the study?
Does exercise echocardiography reveal subclinical cardiac dysfunction in young adult survivors of childhood ALL treated with anthracyclines compared to healthy controls?
Population
23 young adult asymptomatic survivors of childhood acute lymphoblastic leukemia treated with median 120…
Comparison
Exercise stress echocardiography vs 12 healthy controls
Design
Cross-sectional
Follow-up
median 21 years after remission
Authors
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Stress echo may detect subclinical dysfunction in anthracycline-treated ALL survivors; hypothesis-generating and should not yet change practice.
Does exercise echocardiography reveal subclinical cardiac dysfunction in young adult survivors of childhood ALL treated with anthracyclines compared to healthy controls?
Exercise stress echocardiography can unmask subclinical systolic dysfunction in asymptomatic adult survivors of childhood ALL treated with low-dose anthracyclines.
Jarfelt et al. (2007) studied this question.
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