October 13, 2005Journal of Applied Physiology

Isovolumic pressure-to-early rapid filling decay rate relation: model-based derivation and validation via simultaneous catheterization echocardiography

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Population

25 subjects undergoing elective cardiac catheterization and having normal physiology

Design

Cross-sectional

Authors

CCCharles S. ChungWayne State University DADavid M. AjoWashington University in St. Louis SKSándor J. KovácsHUN-REN Institute for Nuclear Research

Discussion

Member takes

Implication

Weak DT-tau correlation cautions against isolated use; supports integrated diastolic models but leaves open prospective validation.

Structured PICO

Population

25 subjects undergoing elective cardiac catheterization and having normal physiology

Intervention

Simultaneous micromanometric left ventricular pressure measurement and transmitral Doppler echocardiography

Outcome

Linear relations relating 1/tau to both peak atrioventricular pressure gradient (kxo) and E-wave-derived viscosity/relaxation (c)surrogate

This study provides a model-based, causal explanation linking the isovolumic mechanism of relaxation and the changing-volume mechanism of early rapid filling, validated by simultaneous catheterization and echocardiography.

Cite This Study

Chung et al. (2005) studied this question.

synapsesocial.com/papers/6a887baf52ebcdde7afcd0ae https://doi.org/10.1152/japplphysiol.00617.2005

View Full Paper

Ask AI

Bookmark

Isovolumic pressure-to-early rapid filling decay rate relation: model-based derivation and validation via simultaneous catheterization echocardiography

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Isovolumic pressure-to-early rapid filling decay rate relation: model-based derivation and validation via simultaneous catheterization echocardiography

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider