Highlights myocardial infarction and subsequent myocardial rupture as a rare but fatal complication in Ehlers-Danlos Syndrome Type IV.
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Alerts to possible myocardial rupture in EDS-IV patients with MI; extends sparse literature but is hypothesis-generating.
Ehlers-Danlos Syndrome Type IV is an illness that often leads to premature death due to arterial rupture or dissection and is characterized by very fragile connective tissue. This report documents the death of a 30-year-old man with Ehlers-Danlos Syndrome Type IV from myocardial rupture and cardiac tamponade following a myocardial infarction. We believe that Ehlers-Danlos Syndrome Type IV contributed to the coronary atherosclerosis and myocardial rupture in this young man and that this disease led indirectly to his death by myocardial infarction, an unusual cause of death in this syndrome.
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Gilchrist et al. (2005) studied this question.
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