What is the clinical evidence from this study?

Study design: Case Report. Population: Ehlers-Danlos syndrome (n=1). Intervention: Ehlers-Danlos syndrome.

What does this research mean for the field?

Ehlers-Danlos syndrome can manifest with severe primary concentric left ventricular hypertrophy and aortic arch narrowing in the absence of aortic valve stenosis. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

January 1, 1972Japanese Heart JournalOpen Access

Cardiovascular Features in a Case of Ehlers-Danlos Syndrome

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Key result

Ehlers-Danlos syndrome case features severe primary concentric LVH and sudden aortic arch narrowing.

Population

1 adult male with Ehlers-Danlos syndrome presenting with anginal pains, systolic murmur, and severe left…

Design

Case_report

Authors

FMF. MagriniClinical Research Management CFCesare FiorentiniCardiac Imaging APA PoleseLuigi Sacco Hospital

Discussion

Member takes

Implication

Suggests possible primary cardiac involvement in Ehlers-Danlos syndrome; leaves open confirmation in larger cohorts.

Study Design

Type

Case Report (n=1)

Multicenter

Structured PICO

Population

A 37-year-old man with Ehlers-Danlos syndrome evaluated for severe left ventricular hypertrophy and aortic arch abnormalities.

Severe concentric left ventricular hypertrophy and aortic arch narrowing can occur in Ehlers-Danlos syndrome, potentially as a primary myocardial and vascular manifestation of the connective tissue disorder.

Limitations

Single case report
The observed cardiovascular abnormalities could be a chance association rather than directly caused by the syndrome
Cardiovascular abnormalities in this syndrome could merely be chance associations

Cite This Study

Magrini et al. (1972) conducted a case report in Ehlers-Danlos syndrome (n=1). Ehlers-Danlos syndrome was evaluated. A 37-year-old man with Ehlers-Danlos syndrome was found to have severe primary concentric left ventricular hypertrophy and sudden narrowing of the aortic arch.

synapsesocial.com/papers/6aa6002986a9fcb249922d4b https://doi.org/10.1536/ihj.13.272

Topics

Cardiomyopathy

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January 1, 1972Japanese Heart JournalOpen Access

Cardiovascular Features in a Case of Ehlers-Danlos Syndrome

View Full Paper

Ask AI

Bookmark

Key result

Ehlers-Danlos syndrome case features severe primary concentric LVH and sudden aortic arch narrowing.

Population

1 adult male with Ehlers-Danlos syndrome presenting with anginal pains, systolic murmur, and severe left…

Design

Case_report

Authors

FMF. MagriniClinical Research Management CFCesare FiorentiniCardiac Imaging APA PoleseLuigi Sacco Hospital

Discussion

Member takes

Implication

Suggests possible primary cardiac involvement in Ehlers-Danlos syndrome; leaves open confirmation in larger cohorts.

Study Design

Type

Case Report (n=1)

Multicenter

Structured PICO

Population

A 37-year-old man with Ehlers-Danlos syndrome evaluated for severe left ventricular hypertrophy and aortic arch abnormalities.

Limitations

Single case report
The observed cardiovascular abnormalities could be a chance association rather than directly caused by the syndrome
Cardiovascular abnormalities in this syndrome could merely be chance associations

Cite This Study

synapsesocial.com/papers/6aa6002986a9fcb249922d4b https://doi.org/10.1536/ihj.13.272

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Topics

Cardiomyopathy

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