Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 10, 2025Tropical Medicine and Infectious DiseaseOpen Access

Analysis revealed the presence of HRSV lineages A.D.2.2.1, A.D.3, B.D.4.1.1, and B.D.E.1, with no previously described mutations in the F protein conferring resistance to Palivizumab and Nirsevimab.

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Limited literature on HRSV in Cabo Verde hinders the study of its epidemiology and evaluation of public health implications.

Population

HRSV isolates from Cabo Verde during 2019 and 2022

Design

Validation and sequencing study

Authors

MRMaría Paula Reyes-ZuluagaJPJosé Antonio Pérez PérezUniversidad de La LagunaWCWilson Correia

Discussion

Loading...

Member takes

Overview

Supports continued local RSV prophylaxis; leaves open need for expanded multi-region surveillance to monitor resistance.

Structured PICO

P
Population
Human Respiratory Syncytial Virus (HRSV) isolates from Cabo Verde (years 2019 and 2022)
I
Intervention
Development and validation of a primer collection for the amplification and sequencing of the G and F genes of HRSV
O
Outcome
Identification of HRSV lineages and detection of mutants in the HRSV F protein conferring resistance to Palivizumab or Nirsevimab

A newly developed primer set successfully identified circulating HRSV lineages in Cabo Verde and confirmed the absence of known resistance mutations to prophylactic therapies.

Cite This Study

Reyes-Zuluaga et al. (2025) studied this question.

synapsesocial.com/papers/6a88fd01d5f4e697bb1317f1https://doi.org/10.3390/tropicalmed10060160
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Genomic evolution of human respiratory syncytial virus during a decade (2013–2023): bridging the path to monoclonal antibody surveillance2024 · 17 citations
  2. 2Epidemiological and phylogenetic characterization of human respiratory syncytial virus associated with severe acute respiratory infections in paediatric patients from 2016 to 2023 in Hangzhou, China2025
  3. 3Genomic characterization of circulating respiratory syncytial virus strains in Lombardy before and after the introduction of nirsevimab prophylaxis2026
  4. 4Evolutionary dynamics of HRSV following the implementation of nirsevimab immunoprophylaxis in Catalonia (2023-2024)2025 · 5 citations
  5. 5Human Respiratory Syncytial Virus Genetic Diversity and Lineage Replacement in Ireland pre- and post-COVID-19 pandemic2024 · 1 citations