IL-1beta and IL-6 are strongly upregulated in the acute phase (first 3-12 hours) after myocardial infarction in rats, suggesting a role in early wound healing and matrix remodeling rather than long-term remodeling.
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Acute IL-1β/IL-6 upregulation in rat MI is hypothesis-generating for early healing; leaves open human translation and timing of interventions.
Alexander Deten (2002) studied this question.
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