Why the study?
Does hypertension and ageing increase atrial arrhythmia inducibility and alter atrial substrate in rats?
Does hypertension and ageing increase atrial arrhythmia inducibility and alter atrial substrate in rats?
Concomitant hypertension plays a greater pathophysiological role than ageing in atrial electrical and structural remodeling, predisposing to atrial fibrillation.
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Hypertension may outweigh aging in driving atrial remodeling and inducibility in rats; leaves open translation to human AF prevention.
Lau et al. (2013) studied this question.
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