Why the study?
Does low-molecular-weight heparin (LMWH) improve prevention and treatment of DVT compared to standard heparin in orthopedic patients?
Population
High-risk orthopedic patients and patients with proximal deep vein thrombosis (DVT)
Comparison
Low-molecular-weight heparin (LMWH) vs Standard heparin
Design
Review
Authors
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May guide LMWH preference in orthopedic DVT management; leaves open need for randomized confirmation of superiority.
Does low-molecular-weight heparin (LMWH) improve prevention and treatment of DVT compared to standard heparin in orthopedic patients?
LMWH offers a more predictable dose response, less bleeding, and the feasibility of home treatment for DVT prevention and management in orthopedic patients compared to standard heparin.
Alexander G.G. Turpie (1997) studied this question.
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