Population
Freshly isolated rat renal structures and rat anterior pituitary cells
Design
Preclinical
Authors
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Animal data on segment-specific Ang II desensitization leave open human relevance; no implications for clinical practice.
Desensitization of Angiotensin II receptors in rat kidneys depends on the proportion of AT1A and AT1B subtypes or cell-specific factors, allowing adaptive biological responses.
Hus-Citharel et al. (2001) studied this question.
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