Population
Rat adrenal gland, kidney, and brain tissues
Design
Preclinical
Authors
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No immediate changes to ARB use; leaves open AT-2 roles in human adrenal and brain function.
This study maps the distinct anatomical distribution of AT-1 and AT-2 receptors in rat tissues, providing a basis for understanding the tissue-specific effects of angiotensin II and its antagonists.
Song et al. (2008) studied this question.
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