What does this research mean for the field?

There is no significant difference in the incidence of infective endocarditis between transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (SAVR), and surgical treatment is associated with lower mortality in TAVI-associated infective endocarditis. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

June 30, 2020Reviews in Cardiovascular MedicineOpen Access

Infective endocarditis after TAVI: a meta-analysis and systematic review of epidemiology, risk factors and clinical consequences

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Why the study?

Increasing surgical and transcatheter heart valve replacements lead to higher prosthetic valve endocarditis, prompting a comparison of infective endocarditis incidence between TAVI and SAVR, along with risk factors and treatment strategies.

Does TAVI compared to SAVR alter the incidence of infective endocarditis in patients requiring aortic valve replacement?

Population

Patients across 68 selected publications

Comparison

TAVI vs SAVR

Design

Meta-analysis and systematic review

Authors

GTGrigore TinicăCardiac Surgery AȚAndrei ȚărușCardiovascular Institute of the South MEMihai F. EnacheGrigore T. Popa University of Medicine and Pharmacy

Discussion

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Implication

Similar IE incidence after TAVI and SAVR; observational data leave open whether surgery improves TAVI-IE survival.

Structured PICO

Does TAVI compared to SAVR alter the incidence of infective endocarditis in patients requiring aortic valve replacement?

Population

Patients undergoing transcatheter aortic valve implantation (TAVI) or surgical valve replacement (SAVR) from 68 pooled publications

Intervention

Transcatheter aortic valve implantation (TAVI)

Comparator

Surgical valve replacement (SAVR)

Outcome

Incidence of infective endocarditis (in-hospital, early, mid-term, and late)hard clinical

TAVI and SAVR carry similar risks of infective endocarditis, though TAVI-IE is associated with high mortality (38.3%) and specific risk factors including male gender, intubation, new pacemaker, and CKD.

Cite This Study

Tinică et al. (2020) studied this question.

synapsesocial.com/papers/6a890b903981116ebf4d29fa https://doi.org/10.31083/j.rcm.2020.02.68

Topics

Transcatheter aortic valve replacement TAVR in low-risk patients Infective endocarditis

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Infective endocarditis after TAVI: a meta-analysis and systematic review of epidemiology, risk factors and clinical consequences

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Infective endocarditis after TAVI: a meta-analysis and systematic review of epidemiology, risk factors and clinical consequences

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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