Why the study?
Does simulated pressure wire drift of ±2 mm Hg affect stenosis categorization using FFR, iFR, and whole-cycle Pd/Pa?
Population
447 coronary stenoses assessed with FFR, iFR, and whole-cycle Pd/Pa
Comparison
Simulated pressure wire drift vs Baseline measurements without simulated drift
Design
Cross-sectional
Authors
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Small pressure wire drift may misclassify stenoses with physiologic indices; leaves open whether routine drift checks alter revascularization decisions.
Does simulated pressure wire drift of ±2 mm Hg affect stenosis categorization using FFR, iFR, and whole-cycle Pd/Pa?
Small amounts of pressure wire drift (±2 mm Hg) can cause substantial stenosis misclassification, with whole-cycle Pd/Pa being more vulnerable to reclassification than FFR and iFR.
Cook et al. (2016) studied this question.
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