Population
Rabbit pulmonary artery (RPA) rings and vascular smooth muscle cells (VSMC)
Design
Preclinical
Authors
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May alter ET(B2)R-mediated pulmonary artery tone during remodeling; leaves open translational relevance to human disease.
The ET(B2) receptor in rabbit pulmonary artery smooth muscle cells undergoes rapid transcriptional down-regulation during in vitro phenotypic modulation.
Owe‐Young et al. (1999) studied this question.
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