A Cytochemical Investigation of Striated Muscle Differentiation in Regenerating Limbs of the Roach, Periplanata Americana1)

The maturation of striated muscle involves a complex series of changes in the chemical morphology of the cell, and for this reason has been a favored system in which to investigate cellular differentiation. Some aspects of the chemical cytology of mammalian striated muscle regeneration have been described by In both cases, the general course of muscle development was similar, particularly if considered at the cellular level rather than at the tissue level. LE GROS-CLARK (1946) established that mammalian striated muscle could only regenerate if the stromal elements and sarcolemmal tubes remained intact and, the later work of GODMAN (1957, 1958) supported this conclusion.