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December 1, 2007Current Opinion in Anaesthesiology

Low-dose aspirin and clopidogrel: how to act in patients scheduled for day surgery

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Why the study?

Should antiplatelet therapy (aspirin and clopidogrel) be maintained or withheld in patients scheduled for day surgery?

Population

Patients on antiplatelet drug treatment scheduled for day surgery

Comparison

Maintaining aspirin therapy and possible… vs Withholding antiplatelet drug treatment

Design

Review

Authors

FSF. ServinAssistance Publique – Hôpitaux de Paris

Discussion

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Implication

May support continuing antiplatelet therapy in low-bleeding-risk ambulatory surgery; leaves open confirmation by prospective RCTs.

Structured PICO

Should antiplatelet therapy (aspirin and clopidogrel) be maintained or withheld in patients scheduled for day surgery?

P
Population
Patients on antiplatelet drug treatment (low-dose aspirin and clopidogrel) scheduled for day surgery (ambulatory surgery)
I
Intervention
Maintaining aspirin therapy and possible antiplatelet drug inhibitors throughout the perioperative period
C
Comparator
Withholding antiplatelet drug treatment
O
Outcome
Bleeding risk and complications resulting from interference with invasive proceduressafety

For most ambulatory surgical procedures with low bleeding risk, it is recommended to maintain aspirin and antiplatelet therapy throughout the perioperative period.

Cite This Study

F. Servin (2007) studied this question.

synapsesocial.com/papers/6a89234de49c960f581fff2dhttps://doi.org/10.1097/aco.0b013e3282f15f95

Topics

Dual antiplatelet therapy
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Perioperative antiplatelet therapy: the case for continuing therapy in patients at risk of myocardial infarction2007 · 322 citations
  2. 2Anticlotting drugs and regional anaesthetic and analgesic techniques2007 · 59 citations
  3. 3Platelet Function and Pharmacologic Inhibition2006 · 21 citations
  4. 4Low‐dose aspirin for secondary cardiovascular prevention – cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation – review and meta‐analysis2005 · 894 citations
  5. 5The safety of endoscopic sphincterotomy in patients receiving antiplatelet agents – a case–control study2006 · 95 citations