December 30, 2013Journal of Interventional Cardiology
Do Outcomes from Transcatheter Aortic Valve Implantation Vary According to Access Route and Valve Type? The UK TAVI Registry
Why the study?
Does access route or valve type affect mortality in patients undergoing TAVI?
Structured PICO
Does access route or valve type affect mortality in patients undergoing TAVI?
P
Population
1,620 patients undergoing transcatheter aortic valve implantation (TAVI) in the UK
I
Intervention
TAVI via transapical (TA) access or subclavian access, or using CoreValve prosthesis
C
Comparator
TAVI via transfemoral (TF) access, or using SAPIEN prosthesis
O
Outcome
Mortality at 30 days, 1 year, and 2 yearshard clinical
In a real-world TAVI registry, transapical access was associated with higher early and late mortality compared to transfemoral access, while valve type (SAPIEN vs. CoreValve) did not influence survival.
Authors
Discussion
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Implication
Transapical access may increase TAVI mortality risk; leaves open causal effects versus selection bias and supports randomized access comparisons.
Cite This Study
Blackman et al. (2013) studied this question.