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May 25, 2012Journal of Interventional Cardiology

Acute and Late Outcomes of Transcatheter Aortic Valve Implantation (TAVI) for the Treatment of Severe Symptomatic Aortic Stenosis in Patients at High‐ and Low‐Surgical Risk

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Why the study?

Does mortality after TAVI correlate with logistic EuroSCORE and delivery approach in patients with severe symptomatic aortic stenosis?

Population

300 patients with severe symptomatic aortic stenosis at high- and low-surgical risk, mean EuroSCORE 24.0

Design

Cohort

Follow-up

1 year

Authors

GSGerhard SchymikInterventional / Structural CardiologyHSHolger SchröfelUniversity of FreiburgJSJan S. SchymikHeidelberg University

Discussion

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Implication

Logistic EuroSCORE predicts post-TAVI mortality; supports risk stratification yet leaves open prospective validation of delivery approach.

Structured PICO

Does mortality after TAVI correlate with logistic EuroSCORE and delivery approach in patients with severe symptomatic aortic stenosis?

P
Population
300 patients with severe symptomatic aortic stenosis at high- and low-surgical risk, mean EuroSCORE 24.0
I
Intervention
Transcatheter Aortic Valve Implantation (TAVI) using Edwards SAPIEN or Medtronic CoreValve via transfemoral (n=174) or transapical (n=126) approach
O
Outcome
Mortality at 30 days and 1 yearhard clinical

In patients undergoing TAVI, mortality correlates significantly with the logistic EuroSCORE, demonstrating that patients with a EuroSCORE <15 have low 30-day mortality and good 1-year outcomes.

Cite This Study

Schymik et al. (2012) studied this question.

synapsesocial.com/papers/6a89267c3d6e0fcd7a28c461https://doi.org/10.1111/j.1540-8183.2012.00729.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Primary isolated aortic valve surgery in octogenarians2010 · 44 citations
  2. 2One-Year Outcomes of Cohort 1 in the Edwards SAPIEN Aortic Bioprosthesis European Outcome (SOURCE) Registry2011 · 530 citations
  3. 3Transcatheter versus Surgical Aortic-Valve Replacement in High-Risk Patients2011 · 6,395 citations
  4. 4Transcatheter aortic valve implantation: predictors of procedural success—the Siegburg–Bern experience2009 · 103 citations
  5. 5The European System for Cardiac Operative Risk Evaluation (EuroSCORE) is not appropriate for withholding surgery in high-risk patients with aortic stenosis: a retrospective cohort study2009 · 71 citations