Highlights the importance of recognizing fever as a trigger that can unmask Brugada syndrome and potentially lead to fatal ventricular arrhythmias.
Clinicians should consider ECG monitoring during fever in at-risk patients; case report leaves open prospective validation of risk and management.
Brugada syndrome is increasingly recognized as a cause of sudden cardiac death. Many of these patients do not get diagnosed due its dynamic and often hidden nature. We have come a long way in understanding the disease process, and its electrophysiology appears to be intimately linked with sodium channel mutations or disorders. The cardiac rhythm in these patients can deteriorate into fatal ventricular arrhythmias. This makes it important for the clinician to be aware of the conditions in which arrhythmogenicity of Brugada syndrome is revealed or even potentiated. We present such an instance where our patient's Brugada syndrome was unmasked by fever.
No takes yet. Share an insight, caveat, or question.
Manohar et al. (2015) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: