What question did this study set out to answer?

To highlight the relationship between low-grade fever and the Brugada pattern in susceptible individuals.

Type 1 Brugada Pattern Triggered by Low-Grade Fever: Implications for Diagnosis and Risk Stratification

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To highlight the relationship between low-grade fever and the Brugada pattern in susceptible individuals.
Multiparametric examination and genetic analysis in a case of febrile Brugada syndrome.
12-lead ECG recordings during subfebrile episodes in a 19-year-old man.
Targeted genetic testing of SCN5A gene conducted.
The patient exhibited ST-segment elevations in leads V1–V3 during febrile episodes.
No disease-causing variants in SCN5A identified through genetic testing.
Low-grade fever demonstrated to induce Brugada type 1 pattern in susceptible patients.

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Case report shows ST-segment elevations in Brugada syndrome, indicating fever can trigger cardiac dysfunction.

Hamza et al. (2026) studied this question.

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