Why the study?
Do mean arterial pressure and rewarming rate during cardiopulmonary bypass affect cognitive decline in patients undergoing cardiac surgery?
Population
237 patients undergoing cardiac surgery
Design
Cohort
Follow-up
predischarge
Authors
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Elderly patients may be more susceptible to low MAP and rapid rewarming for cognitive decline after cardiac surgery; hypothesis-generating for targeted trials.
Do mean arterial pressure and rewarming rate during cardiopulmonary bypass affect cognitive decline in patients undergoing cardiac surgery?
Hypotension and rapid rewarming during cardiopulmonary bypass contribute significantly to early cognitive dysfunction specifically in elderly patients undergoing cardiac surgery.
Newman et al. (1995) studied this question.
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