Why the study?
Do large hypotensive stresses during cardiopulmonary bypass increase the risk of postoperative cerebral dysfunction in patients undergoing cardiac surgery?
Population
75 patients undergoing cardiac operations with the assistance of cardiopulmonary bypass (CPB)
Comparison
Large hypotensive stresses during CPB vs No large hypotensive stresses, or comparable…
Design
Cohort
Follow-up
Postoperative period
Authors
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Large hypotensive stresses during CPB were associated with cerebral dysfunction; hypothesis-generating and requires prospective confirmation before practice change.
Do large hypotensive stresses during cardiopulmonary bypass increase the risk of postoperative cerebral dysfunction in patients undergoing cardiac surgery?
Hypotension during cardiopulmonary bypass can lead to severe postoperative cerebral dysfunction, particularly in older patients or those with prior cerebrovascular insufficiency.
Stockard et al. (1974) studied this question.
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