Why the study?
Does the administration of salt solutions during operation affect postoperative excretion of salt in surgical patients?
Does the administration of salt solutions during operation affect postoperative excretion of salt in surgical patients?
The study investigates the effects of intraoperative salt solution administration on postoperative salt excretion to address the concept of postoperative renal salt intolerance.
This is the authors' abstract. We don't add key points for this paper.
The pattern of postoperative excretion of salt and water has been described by many investigators, and reviewed by Moyer1and Moore.2Previous studies have led to the concept of renal intolerance to salt and water in the postoperative period. In many centers, practical application of this concept has resulted in no salt solutions being given to surgical patients during or, for a limited time, after elective operation. This study is designed for observation of the effects of salt solutions given during operation on the postoperative excretion of salt. In this laboratory, using isotopic methods, a significant fall in effective extracellular fluid, greater than that lost as plasma (blood loss), has been observed to occur during the operative period.3In this study the amount of extracellular fluid loss was correlated with the degree of operative trauma. Administration of salt solutions during operation would represent replacement of the acquired
Answers are grounded in this paper and cite their sources.
Should not yet alter perioperative fluid strategies; leaves open effects of intraoperative salt on postoperative excretion.
No takes yet. Share an insight, caveat, or question.
Tom Shires (1962) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: