Why the study?
Does isotonic sodium chloride inhibit the aldosterone response to surgery in healthy women undergoing cholecystectomy compared to 5% glucose in water?
Population
12 otherwise healthy women undergoing cholecystectomy
Comparison
Isotonic sodium chloride administered during an… vs 5 per cent glucose in water administered during…
Design
Other
Follow-up
22 hours
Authors
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Saline may blunt aldosterone response to surgery; hypothesis-generating and should not yet change fluid restriction practices.
Does isotonic sodium chloride inhibit the aldosterone response to surgery in healthy women undergoing cholecystectomy compared to 5% glucose in water?
Administration of isotonic saline during surgery inhibits the aldosterone response, questioning the rationale of saline restriction during and after surgery.
Engquist et al. (1978) studied this question.
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