Why the study?
Does succinylcholine administration increase muscle injury markers and postoperative pain more in statin users compared to nonusers?
Population
70 patients undergoing general anesthesia requiring intubation
Comparison
Succinylcholine 1.5 mg/kg for intubation in… vs Succinylcholine 1.5 mg/kg for intubation in…
Design
Cohort
Follow-up
24 hours
Authors
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Small myoglobin rise after succinylcholine in statin users appears clinically insignificant; leaves open confirmation in randomized trials.
Does succinylcholine administration increase muscle injury markers and postoperative pain more in statin users compared to nonusers?
Succinylcholine administration in statin users causes a small, clinically insignificant increase in myoglobin and fasciculations compared to nonusers, without worsening postoperative muscle pain.
Turan et al. (2011) studied this question.
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