Population
Rats with acute myocardial infarction (AMI model)
Comparison
Acute myocardial infarction induction vs Sham control
Design
Preclinical
Authors
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Hypothesis-generating for miRNA biomarkers in experimental AMI; leaves open human validation and clinical relevance.
Acute myocardial infarction alters the expression of specific microRNAs in rat myocardium, suggesting potential novel biomarkers for AMI.
Shi et al. (2010) studied this question.
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