Why the study?
Does sublingual nitroglycerin affect the cardio-ankle vascular index differently in patients with coronary artery disease compared to normal controls?
Population
56 subjects, comprising normal controls with no medical history or regular medications and patients with…
Comparison
Single sublingual administration of… vs Normal controls compared to CAD patients.
Design
Cohort
Follow-up
20 minutes
Authors
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Similar CAVI response to nitroglycerin in CAD patients and controls; supports preserved smooth muscle NO sensitivity but leaves open clinical relevance.
Does sublingual nitroglycerin affect the cardio-ankle vascular index differently in patients with coronary artery disease compared to normal controls?
Sublingual nitroglycerin decreases arterial stiffness as measured by CAVI similarly in both normal controls and CAD patients on medication, suggesting preserved smooth muscle response to nitric oxide in CAD.
Shimizu et al. (2016) studied this question.
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