Why the study?
Is the factor V Leiden mutation associated with cerebral palsy and vascular thrombosis in children?
Population
224 children with cerebral palsy and their mothers, including 57 children with imaging evidence of vascular…
Comparison
Testing for factor V Leiden (fVL) mutation vs Children with CP and other imaging findings and…
Design
Case-control
Authors
Loading...
fVL frequency exceeds population norms without group differences; leaves open contributory role in pediatric cerebral palsy and thrombosis.
Is the factor V Leiden mutation associated with cerebral palsy and vascular thrombosis in children?
The factor V Leiden mutation frequency is higher in children with cerebral palsy and vascular thrombosis compared to the general population, suggesting a potential contributory role to thrombophilia in this population.
Halliday et al. (2005) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: