February 19, 2008Proceedings of the National Academy of SciencesOpen Access

Independent genesis of chimeric TRIM5-cyclophilin proteins in two primate species

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CVCésar A. VirgenMemorial Sloan Kettering Cancer Center ZKZerina KratovacIcahn School of Medicine at Mount Sinai PBPaul D. BieniaszHoward Hughes Medical Institute

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Implication

TRIMCyp fusion reveals primate-specific retroviral restriction; leaves open whether analogous mechanisms shape human susceptibility or offer therapeutic targets.

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Key points are not available for this paper at this time.

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Virgen et al. (2008) studied this question.

synapsesocial.com/papers/6a892fa43aa2d8278f761351 https://doi.org/10.1073/pnas.0709258105

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Implication

TRIMCyp fusion reveals primate-specific retroviral restriction; leaves open whether analogous mechanisms shape human susceptibility or offer therapeutic targets.

Independent genesis of chimeric TRIM5-cyclophilin proteins in two primate species

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Member takes

Implication

Key Points

Cite This Study

Independent genesis of chimeric TRIM5-cyclophilin proteins in two primate species

Discussion

Member takes

Implication

Key Points

Cite This Study

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