April 1, 2001AJP Heart and Circulatory Physiology

Differential dynamic baroreflex regulation of cardiac and renal sympathetic nerve activities

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Population

Anesthetized, vagotomized, and aortic-denervated rabbits (n=9)

Comparison

Random perturbation of intracarotid sinus pressure vs Comparison of responses between cardiac…

Design

Preclinical

Authors

TKToru KawadaUniversity of Chichester TSToshiaki ShishidoNational Cerebral and Cardiovascular Center MIMasashi InagakiNational Cerebral and Cardiovascular Center

Discussion

Member takes

Implication

Suggests distinct brainstem baroreflex processing for CSNA versus RSNA in animals; leaves open human translation.

Structured PICO

Population

Anesthetized, vagotomized, and aortic-denervated rabbits (n=9)

Intervention

Random perturbation of intracarotid sinus pressure (CSP)

Comparator

Comparison of responses between cardiac sympathetic nerve activity (CSNA) and renal sympathetic nerve activity (RSNA)

Outcome

Neural arc transfer function from CSP to CSNA and RSNA (increasing slope of transfer gain between 0.03 and 0.3 Hz)surrogate

Dynamic baroreflex activation exerts differential effects on cardiac and renal sympathetic nerve activities, indicating distinct central processing in the brain stem.

Cite This Study

Kawada et al. (2001) studied this question.

synapsesocial.com/papers/6a8930e1c9c00c271ba2affc https://doi.org/10.1152/ajpheart.2001.280.4.h1581

View Full Paper

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Differential dynamic baroreflex regulation of cardiac and renal sympathetic nerve activities

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Differential dynamic baroreflex regulation of cardiac and renal sympathetic nerve activities

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider