Uniformity in dynamic baroreflex regulation of left and right cardiac sympathetic nerve activities

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Population

9 anesthetized, vagotomized, and aortic-denervated rabbits

Design

Preclinical

Authors

Discussion

No laterality in rabbit cardiac sympathetic baroreflex responses; hypothesis-generating for human asymmetry and requires clinical translation.

Population

9 anesthetized, vagotomized, and aortic-denervated rabbits

Intervention

Random perturbation of intracarotid sinus pressure (CSP) in both carotid sinus regions

Outcome

Baroreflex neural arc transfer function from CSP to left (LSNA) and right (RSNA) cardiac sympathetic nerve activitiessurrogate

Dynamic and static baroreflex regulation of left and right cardiac sympathetic nerve activities show no functional laterality in a rabbit model.

Kawada et al. (2003) studied this question.

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No laterality in rabbit cardiac sympathetic baroreflex responses; hypothesis-generating for human asymmetry and requires clinical translation.