July 1, 2003AJP Regulatory Integrative and Comparative Physiology

Dynamics of sympathetic baroreflex control of arterial pressure in rats

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Population

11 halothane-anesthetized rats

Design

Preclinical

Authors

TSTakayuki SatoKurashiki Central Hospital TKToru KawadaUniversity of Chichester MIMasashi InagakiNational Cerebral and Cardiovascular Center

Discussion

Member takes

Implication

Rat baroreflex findings indicate mechanoneural compensation for neuromechanical lag; extends dynamic models but leaves open human translation.

Structured PICO

Population

11 halothane-anesthetized rats

Intervention

Random alteration of carotid sinus baroreceptor pressure (BRP) using a white noise approach

Outcome

Transfer functions from BRP to sympathetic nerve activity (SNA), from SNA to systemic arterial pressure (SAP), and from BRP to SAPsurrogate

Quantitative estimation of baroreflex dynamics reveals that the mechanoneural arc compensates for the sluggish response of the neuromechanical arc in rats.

Cite This Study

Sato et al. (2003) studied this question.

synapsesocial.com/papers/6a1cffeb61cd17b5e22f13a7 https://doi.org/10.1152/ajpregu.00692.2001

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Implication

Rat baroreflex findings indicate mechanoneural compensation for neuromechanical lag; extends dynamic models but leaves open human translation.

Dynamics of sympathetic baroreflex control of arterial pressure in rats

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Dynamics of sympathetic baroreflex control of arterial pressure in rats

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider