Why the study?
Does arterial baroreflex control of renal sympathetic nerve activity differ between spontaneously hypertensive rats and normotensive rats?
Population
Spontaneously hypertensive rats and normotensive Wistar-Kyoto rats anesthetized with pentobarbital sodium
Comparison
Random perturbation of aortic pressure using a… vs Wistar-Kyoto rats serving as normotensive controls
Design
Preclinical
Authors
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Similar baroreflex control of renal SNA in SHR versus WKY; leaves open translation to human hypertension.
Does arterial baroreflex control of renal sympathetic nerve activity differ between spontaneously hypertensive rats and normotensive rats?
Dynamic or frequency-dependent characteristics of arterial baroreflex control of renal sympathetic nerve activity are not altered in spontaneously hypertensive rats compared with normotensive rats.
Harada et al. (1992) studied this question.
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