SummaryBiochemical studies on the influence of ascorbic acid deficiency on the concentration of collagen and acid mucopolysaccharides in connetive tissues were carried out on guinea pig carcasses. The concentration of hydroxyproline, representing the concentration of collagen, was not significantly changed during ascorbic acid deficiency. The influence of ascorbic acid on collagen synthesis is discussed. During ascorbic acid deficiency, the concentration of hexosamine, indicating the content of mucopolysaccharides, and of uronic acid, representing acid mucopolysaccharides, showed no significant alterations in guinea pig carcasses.
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Bendt Kirchheiner (1965) studied this question.
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