Why the study?
Does breathing aerosols propelled with fluorinated hydrocarbons cause cardiac arrhythmias in dogs?
Population
16 dogs
Design
Preclinical
Authors
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May induce fatal arrhythmias in canines independent of hypoxia; hypothesis-generating for human aerosol safety.
Does breathing aerosols propelled with fluorinated hydrocarbons cause cardiac arrhythmias in dogs?
Fluorinated hydrocarbon aerosols can induce severe cardiac arrhythmias, including asystole and ventricular fibrillation, in a canine model independent of hypoxia.
Nancy C. Flowers (1972) studied this question.
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