Why the study?
Are angiotensin II receptor antagonists as effective as ACE inhibitors with a better side-effect profile in patients with hypertension, heart failure, and chronic renal disease?
Population
Patients with hypertension, heart failure (HF), and chronic renal disease (CRD)
Comparison
Angiotensin II (AII) receptor antagonists vs Angiotensin converting enzyme (ACE) inhibitors
Design
Review
Authors
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ARBs may serve as cough-free alternatives to ACE inhibitors; leaves open need for randomized outcome trials in heart failure and CKD.
Are angiotensin II receptor antagonists as effective as ACE inhibitors with a better side-effect profile in patients with hypertension, heart failure, and chronic renal disease?
Angiotensin II receptor antagonists are effective alternatives to ACE inhibitors for hypertension, heart failure, and chronic renal disease, offering an improved side-effect profile without persistent dry cough.
David J. Dzielak (1998) studied this question.
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