Why the study?
Do angiotensin II receptor antagonists improve outcomes compared to ACE inhibitors or placebo in patients with congestive heart failure?
Population
Patients with congestive heart failure (CHF)
Comparison
Angiotensin II receptor antagonists vs Placebo or angiotensin-converting enzyme…
Design
Review
Authors
Loading...
ARBs remain acceptable alternatives for ACEI-intolerant HF patients; leaves open first-line equivalence versus ACEIs in broader populations.
Do angiotensin II receptor antagonists improve outcomes compared to ACE inhibitors or placebo in patients with congestive heart failure?
ACE inhibitors remain the first-line treatment for CHF, with ARBs serving as an acceptable alternative for patients intolerant to ACE inhibitors.
Martineau et al. (2001) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: