Population
Decerebrated rats in which one femoral artery had been occluded 72 h previously and control rats whose…
Comparison
Injection of the mu-opioid receptor agonist… vs Baseline and control rats with freely perfused…
Design
Preclinical
Authors
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Peripheral mu-opioid agonism may blunt exercise pressor reflex in rat PAD models; hypothesis-generating with no clinical implications yet.
Stimulation of peripheral mu-opioid receptors attenuates the exercise pressor reflex in rats with chronic femoral artery occlusion.
Tsuchimochi et al. (2010) studied this question.
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