Why the study?
Does RT-PCR improve the detection and typing of Enteroviruses in patients with acute aseptic meningitis compared to conventional methods?
Population
52 cases of acute aseptic meningitis that occurred from March 2003 to April 2005
Comparison
5'NCR and VP1-2A RT-PCR with sequence analysis vs Conventional methods (viral culture)
Design
Cross-sectional
Authors
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May support faster enterovirus detection in aseptic meningitis; hypothesis-generating and should not yet change practice.
Does RT-PCR improve the detection and typing of Enteroviruses in patients with acute aseptic meningitis compared to conventional methods?
RT-PCR with sequence analysis is superior to conventional viral culture for the rapid diagnosis and typing of enterovirus meningitis.
Dumaidi et al. (2006) studied this question.
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