Why the study?
Are higher plasma sodium levels associated with increased blood pressure and mortality in a healthy adult population?
Population
97,009 adult subjects undergoing health checkups between 1995-2009
Comparison
Higher plasma sodium levels vs Lower plasma sodium levels
Design
Cohort
Follow-up
median 4.2 years
Authors
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pNa ≥145 mM/L was associated with mortality in women ≥50 years; hypothesis-generating and requires prospective confirmation before clinical consideration.
Are higher plasma sodium levels associated with increased blood pressure and mortality in a healthy adult population?
Higher plasma sodium levels are associated with increased blood pressure and, particularly in older women, a higher risk of all-cause mortality.
Oh et al. (2013) studied this question.
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