Attenuation of cardiac remodelling by endocardial injection of erythropoietin: ultrasonic strain-rate imaging in a model of hibernating myocardium

13 pigs with hibernating myocardium induced by chronic vessel occlusion via an ameroid constrictor placed around the circumflex artery

10,000 U erythropoietin (EPO) injected into the ischemic region using a NOGA-guided transendocardial catheter

Placebo injected into the ischemic region

Regional radial function (peak systolic strain-rates, systolic strains, and post-systolic strains) during dobutamine stress echocardiography and myocardial fibrosissurrogate