June 1, 1979Cancer
Prognostic significance of alkaline phosphatase measurements in patients with osteogenic sarcoma receiving chemotherapy
Why the study?
Do elevated preoperative alkaline phosphatase levels predict recurrence in patients with osteogenic sarcoma receiving chemotherapy?
Population
30 patients with osteogenic sarcoma receiving chemotherapy
Comparison
Elevated preoperative alkaline phosphatase levels vs Normal preoperative alkaline phosphatase levels
Design
Cohort
Follow-up
January 1975 to August 1977
Authors
Discussion
Loading...
Member takes
Implication
Elevated preoperative alkaline phosphatase may identify higher recurrence risk in osteogenic sarcoma; hypothesis-generating and should not yet change practice.
Structured PICO
Do elevated preoperative alkaline phosphatase levels predict recurrence in patients with osteogenic sarcoma receiving chemotherapy?
P
Population
30 patients with osteogenic sarcoma receiving chemotherapy
I
Intervention
Elevated preoperative alkaline phosphatase levels
C
Comparator
Normal preoperative alkaline phosphatase levels
O
Outcome
Recurrence of osteogenic sarcomahard clinical
Elevated preoperative alkaline phosphatase levels correlate with a poor prognosis and higher recurrence rate in patients with osteogenic sarcoma receiving chemotherapy.
Cite This Study
Thorpe et al. (1979) studied this question.