Population
Normal and bilaterally cryptorchid rats, and cultured rat anterior pituitary cells
Comparison
Induction of bilateral cryptorchidism vs Sham-operated controls / normal animals
Design
Preclinical
Follow-up
up to 6 weeks
Authors
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Rat model supports inhibin-FSH feedback; leaves open human translation and therapeutic relevance.
The study validates an in vitro bioassay for inhibin and demonstrates that testicular inhibin levels inversely correlate with serum FSH and LH in cryptorchid rats, supporting its role in physiological feedback regulation.
Au et al. (1983) studied this question.
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