Why the study?
Is epinephrine-induced platelet aggregation influenced by genetic factors in healthy adult males?
Population
Healthy adult male twin pairs (17 monozygotic, 15 dizygotic)
Comparison
Epinephrine-induced platelet aggregation testing vs Monozygotic vs dizygotic twins
Design
Cohort
Authors
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Supports genetic influence on epinephrine-induced platelet aggregation; leaves open relevance to cardiovascular outcomes or therapy.
Is epinephrine-induced platelet aggregation influenced by genetic factors in healthy adult males?
Genetic factors appear to influence epinephrine-induced platelet aggregation, though this phenomenon is not related to the number of alpha-adrenergic binding sites on platelets.
Gaxiola et al. (1984) studied this question.
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