Why the study?
Cardiovascular autonomic dysfunction remains a silent complication in individuals at high risk of diabetes, prompting investigation into the impact of week-long heart rate variability on cardiovascular events and mortality.
Does lower week-long heart rate variability (HRV) predict major adverse cardiovascular events, heart failure, and all-cause mortality in people at high risk of diabetes?
Population
1,627 participants at high risk of diabetes from the ADDITION-PRO study
Comparison
Week-long heart rate variability (SDNN proxy) and mean heart rate levels
Design
Prospective cohort study
Follow-up
11-year follow-up
Authors
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Lower week-long HRV was associated with higher MACE, HF, and mortality risk; leaves open whether multiday monitoring refines stratification in high-diabetes-risk adults.
Does lower week-long heart rate variability (HRV) predict major adverse cardiovascular events, heart failure, and all-cause mortality in people at high risk of diabetes?
Lower week-long heart rate variability is significantly associated with an increased risk of MACE, heart failure, and all-cause mortality in individuals at high risk for diabetes.
Schaarup et al. (2024) studied this question.
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